The Role of Chromosome Missegregation in Cancer Development: A Theoretical Approach Using Agent-Based Modelling
Figure 5
The average ratio of apoptosis to division genes.
These graphs show the tendency of reducing the number of apoptosis genes and increasing the number of division genes with respect to time across different scenarios: A. Surgery Scenario, B. Chemotherapy Scenario and C. Combination of both treatments (Surgery followed by Chemotherapy). The dark line is the median of the samples and the shadowed area represents the variance. Interventions were carried out at time step zero. The reported slopes were measured taking into account 25 time steps after each therapy.