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Porous Chitosan Scaffolds with Embedded Hyaluronic Acid/Chitosan/Plasmid-DNA Nanoparticles Encoding TGF-β1 Induce DNA Controlled Release, Transfected Chondrocytes, and Promoted Cell Proliferation

Figure 2

Gel electrophoresis of HA/CS/pTGF-β1 nanoparticles, digests, and control samples.

Lane A shows the DNA molecular weight marker. Lane B shows HA/CS/pTGF-β1 nanoparticles. Lane C shows normal naked pTGF-β1. Lane D shows HA/CS/pTGF-β1 nanoparticles digested by DNase I. Lane E shows naked pTGF-β1 digested by DNase I. Lane F shows HA/CS/pTGF-β1 nanoparticles digested by chitosanase (2.78 µg/µL).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0069950.g002