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Efficacy of Influenza Vaccination and Tamiflu® Treatment – Comparative Studies with Eurasian Swine Influenza Viruses in Pigs

Figure 2

Influence of vaccination and Tamiflu® treatment on antibody kinetics in pigs challenged with A/swine/Potsdam/15/1981 (H1N1/1981) virus.

Hemagglutination inhibition assays were performed with serum from pigs vaccinated with RESPIPORC® FLU3 (A), pigs treated with Tamiflu® (B), and untreated pigs (C). Geometric mean and standard deviation of antibody titres determined in serum samples of 10 vaccinated and Tamiflu®-treated or 12 control animals/ /day are shown until day 2 p.i. and 5 or 7 from day 3–10 p.i., respectively. Mann-Whitney-U-test was used to calculate p statistical probability: *p<0.05, **p<0.01, ***p<0.001. Only significant differences are shown. The detection limit of HI antibody titre determination is shown as dotted line.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0061597.g002