Selenium and Selenoprotein Deficiencies Induce Widespread Pyogranuloma Formation in Mice, while High Levels of Dietary Selenium Decrease Liver Tumor Size Driven by TGFα
Figure 1
Pyogranulomatous inflammation of the small intestine.
Cross section showing diffuse pyogranulomatous inflammation involving the mucosa and muscularis: Areas of highly populated pyogranulomous inflammation (PG), overlying villi of the mucosa are shortened (white arrow) and fused (black arrow) and the crypts (C) are hyperplastic (shown at 4X magnification). Details of processing and staining of the tissue are provided in Materials and Methods.