Antineoplastic Effects of α-Santalol on Estrogen Receptor-Positive and Estrogen Receptor-Negative Breast Cancer Cells through Cell Cycle Arrest at G2/M Phase and Induction of Apoptosis
Figure 3
Effect of α-santalol on cell cycle progression in MCF-7 cells.
Cells were treated with DMSO (control) or 25–75 µM of α-sanatlol for 12 and 24 h, stained with propidium iodide and distribution of cells in different phases of cell cycle were analyzed by flow cytometer. Histograms representing the fluorescence pattern for cell cycle distribution in different treatments are shown for 12 h (A) and 24 h (B). The percentage of cells in each cell cycle phases after 12 h and 24 h respectively are shown in (C) and (D). Data shown here are representative of those having similar results.