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Ultrasound-Mediated Stimulation of Microbubbles after Acute Myocardial Infarction and Reperfusion Ameliorates Left-Ventricular Remodelling in Mice via Improvement of Borderzone Vascularization

Figure 5

Histological analyses.

Myocardial scar formation was determined by means of histomorphometry. (A) Representative images of short axis mouse heart sections stained with picrosirius-red and fast-green without (left) and with (right) UMS-treatment. The collagenous tissue is coloured red whereas myocardium is green. (B) UMS-treated mice demonstrated a significantly lower collagenous scar burden compared to control mice.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0056841.g005