Genetic Determinants of Phosphate Response in Drosophila
Figure 2
Phosphate supplementation or inhibitors of phosphate uptake influences adult life span.
Median life span of adult y w males cultured on standard medium (SM): Control (C, n = 550), 30 mM sodium phosphate (P30, n = 465), 30 mM sodium sulfate (S30, n = 245), 1% sevelamer (Sev1, n = 207), 1 mM phosphonoformic acid (PFA1, n = 130), and the combinations: Sev1+P30 (n = 115), PFA1+P30 (n = 137), or defined medium (DM) supplemented with 1.5, 27, or 53 mM sodium phosphate (P1.5, n = 202; P27, n = 200; P53, n = 194). P<0.005 was used to test for multiple comparisons between eleven treatments.