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Adhesion of Annexin 7 Deficient Erythrocytes to Endothelial Cells

Figure 6

Correlation between phosphatidylserine exposure and dynamic adhesion of erythrocytes to endothelial cells under arterial shear stress.

Arithmetic means ± SEM (n = 6−8) of the erythrocytes adhering to HUVEC as a function of the percentage erythrocytes binding annexin V. The erythrocytes from annexin7-deficient mice (anx7−/−, closed symbols) and their wild type control mice (anx7+/+, open symbols) were left without pretreatment (circles), or pretreated 30 minutes with 1 µM ionomycin (triangles), 12 hours with glucose-depleted Ringer (squares) or 2 hours with hyperosmotic shock by addition of 550 mM sucrose (diamonds).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0056650.g006