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Systematic Review of HIV Transmission between Heterosexual Serodiscordant Couples where the HIV-Positive Partner Is Fully Suppressed on Antiretroviral Therapy

Figure 2

Forest plots of HIV transmission rates per 100 person-years with and without transmissions with unconfirmed viral suppression at the time of suppression.

Footnote:The first forest plot is the summary of HIV transmission rates per 100 person-years with 95% confidence interval for 6 studies with confirmed and unconfirmed viral suppression at time of transmission. The second forest plot is the sensitivity analysis of the 6 studies with confirmed and unconfirmed viral suppression at the time of transmission with forest plot of the summary of HIV transmission rates per 100 person-years with 95% confidence interval reporting on HIV transmission when HIV-positive partner on combination antiretroviral therapy had confirmed viral suppression, omitting transmissions occurring with known or unconfirmed detectable viral loads at the time of transmission (i.e. 3 studies had 4 transmissions with known or unconfirmed detectable viral loads and these transmissions were excluded, while leaving the rest of data in the analysis).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0055747.g002