Genetic and Pharmacological Targeting of CSF-1/CSF-1R Inhibits Tumor-Associated Macrophages and Impairs BRAF-Induced Thyroid Cancer Progression
Figure 5
PTC regression following treatment with DT in Tg-Braf/Ccr2-DTR mice.
A) Weight of thyroids of control and DT-treated Tg-Braf/Ccr2-DTR mice after 10 day treatment with intraperitoneal DT on alternate days. * p<0.01. B–C) Representative sections with the indicated stains. F) Quantification of Ki67 and TUNEL positive staining using Metamorph data analysis. Ki67 p<0.04; TUNEL p<0.01.