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Two Weeks of Metformin Treatment Enhances Mitochondrial Respiration in Skeletal Muscle of AMPK Kinase Dead but Not Wild Type Mice

Figure 5

HAD and CS activity in TA muscles from WT and KD mice treated with metformin or saline for two weeks.

White and black bars shows results from saline treated and metformin treated mice respectively. A: HAD activity. B: CS activity. *: Indicates significant difference between genotype (P<0.05), N = 12–17. Values are S.E.M.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0053533.g005