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Mice Deficient in Urokinase-Type Plasminogen Activator Have Delayed Healing of Tympanic Membrane Perforations

Figure 6

Immunohistochemistry for neutrophils in the open TMs in WT (A), tPA−/− (B), uPA−/− (C) mice and the only closed TM in uPA−/− (D) mice at day 9 after perforation.

Arrows indicate neutrophil staining. Scale bar, 200 µm. EEC, external ear canal; MEC, middle ear cavity; TM, tympanic membrane.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0051303.g006