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Inhibition of PTEN Gene Expression by Oncogenic miR-23b-3p in Renal Cancer

Figure 6

Western analysis of apoptosis and invasion genes after knock down of miR-23b-3p in A-498 cells.

A) Expression of PTEN, PI3-kinase, Akt and IL-32 in A-498 cells, compared to negative control. GAPDH was used as a normalizing control. B) Quantitative data for Western blot analysis. PTEN was up regulated, whereas PI3-kinase, Akt and IL-32 expression were down regulated.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0050203.g006