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Use of Four Next-Generation Sequencing Platforms to Determine HIV-1 Coreceptor Tropism

Figure 3

Comparison of the frequency of variants across NGS platforms.

The heights of the bars represent the combined frequency of V3 variants detected by the NGS platforms 454™, Illumina®, PacBio®, and Ion Torrent™ prior to filtering. The colors within each bar denote the proportional contribution made by each platform after normalization based on coverage. Insets show low frequency variants up to a maximum of 20 unique sequences.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0049602.g003