Single Nucleotide Polymorphism rs17849071 G/T in the PIK3CA Gene Is Inversely Associated with Follicular Thyroid Cancer and PIK3CA Amplification
Figure 1
Single nucleotide polymorphism rs17849071 in intron 9 of the PIK3CA gene.
Shown in Figure 1A is the homozygous genotype of the major allele T at rs1784907, representing the 105th nucleotide of intron 9 of the PIK3CA gene (counting from the first nucleotide of the intron downstream). Figure 1B shows the heterozygous genotype of minor allele G and major allele T at rs17849071. Shown in Figure 1C is a family in which several members, involving two generations, harbor the heterozygous genotype rs17849071G/T (filled symbols).