Dose-Related Estrogen Effects on Gene Expression in Fetal Mouse Prostate Mesenchymal Cells
Figure 1
Cluster analysis of estrogen-responsive genes in fetal UGS mesenchyme cells after estrogen treatment with the two lower doses, showing strong separation of responses to control, 10 pM E2, and 100 pM E2 treatments. Based on clustering, genes were identified as falling into one of 7 groups that differed in their responses to low-dose E2.