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Comparison of Suprachoroidal Drug Delivery with Subconjunctival and Intravitreal Routes Using Noninvasive Fluorophotometry

Figure 2

Representative fluorophotometry scans attained using Fluorotron Masterâ„¢ in Sprague Dawley rat eye.

Scans are for (A) blank eye showing autofluorescence, (B) eyes immediately after injection of NaF in suprachoroidal, posterior subconjunctival, or vitreous region, (C) eyes 30 minutes after injection of NaF in suprachoroidal, posterior subconjunctival, or vitreous region. Data in panel A is an average for n = 6, and in B and C it is an average for n = 4. Representative time dependent scans after injection of NaF in (D) suprachoroidal, (E) posterior subconjunctival, and (F) vitreous regions are also shown. Blank eye scan shows the autofluorescence of choroid-retina, lens, and cornea regions.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0048188.g002