The Prognostic Value of BRAF Mutation in Colorectal Cancer and Melanoma: A Systematic Review and Meta-Analysis
Figure 2
Random effect model of Log hazard ratio (LogHR) with 95% confidence interval for studies comparing the effect of BRAF-V600E mutation on overall survival of colorectal cancer patients.
A LogHR <0 implies a survival benefit for patients with BRAF mutation. The square size indicates the power of each study in meta-analysis based on the number of patients in that study. The center of diamond shape at the lowest part indicates the combined LogHR for meta-analysis and its extremities the 95% confidence interval.