Reactive Oxygen Species in Unstimulated Hemocytes of the Pacific Oyster Crassostrea gigas: A Mitochondrial Involvement
Figure 1
Commonly accepted non-mitochondrial pathways involved in the production of major reactive oxygen species in stimulated bivalve molluscs’ hemocytes, outside the cell membrane (left) and inside phagocytic vacuole (right).
Molecular targets of inhibitors (grey boxes) are indicated. NO, nitric oxide; ONOO−, peroxynitrite; O2−, superoxide; H2O2, hydrogen peroxide; HOCl, hypochloride; NOS, nitric oxide synthase; SOD, superoxide dismutase; MPO, myeloperoxidase. Adapted from Donaghy et al., 2009 [2].