Impact of Corticosterone Treatment on Spontaneous Seizure Frequency and Epileptiform Activity in Mice with Chronic Epilepsy
Figure 3
Individual seizure timelines of epileptic animals receiving vehicle first.
Periods of vehicle and CORT treatment are highlighted in blue and red, respectively, while baseline periods are left white. Bars denote the number of seizures on a given day. One animal exhibited seizures only during CORT treatment (E), while 2 animals (A & C) exhibited seizures primarily during periods of vehicle and CORT treatment. The remaining four animals showed no compelling correlation between seizure incidence and treatment, and overall there was no significant effect of treatment on seizure frequency.