DNA Vaccination Partially Protects against African Swine Fever Virus Lethal Challenge in the Absence of Antibodies
Figure 3
pCMV-sHAPQ induces specific T-cell responses in pigs.
PBMCs obtained before ASFV challenge from pigs immunized with pCMV, pCMV-PQ or pCMV-sHAPQ (immunized three or four times), were in vitro stimulated with media (negative control), with the E75 ASFV isolate (105 HAU50/ml), with a mix of the p54, p30 and HA ASFV proteins (6 μg/ml of each one) or with each one of these proteins individually. Values shown correspond to the average number of IFNγ-secretory cells detected per million of PBMCs. Standard deviations found within each group are also represented.