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Decreased Circulating C3 Levels and Mesangial C3 Deposition Predict Renal Outcome in Patients with IgA Nephropathy

Figure 6

Kaplan-Meier analyses of cumulative renal survival of patients with IgA nephropathy based on (A) serum C3 level and (B) mesangial C3 deposition.

(A) A 10-year renal survival rate was significantly lower in patients with C3 levels <90 mg/dl than those with C3 levels ≥90 mg/dl (P = 0.006). (B) A 10-year survival in patients with 2+ and 3+ mesangial deposition of C3 was lower than in those without C3 deposition (P = 0.04).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0040495.g006