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A Novel Magnetic Nanoparticle Drug Carrier for Enhanced Cancer Chemotherapy

Figure 5

Tumor growth curves of H22 tumor –bearing mice model that received different treatments indicated.

Effective inhibition of the tumor growth can be seen resulting from the DOX-PGMNPs and DOX-PGMNPs-M treatment strategies. The same doxorubicin dose was injected to H22 tumor –bearing mice model for DOX, DOX-PGMNPs and DOX-PGMNPs-M. The same volume physiologic saline solution injected to H22 tumor –bearing mice model as control. *p<0.05; **p<0.01 compared with controls using Student's unpaired t-test.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0040388.g005