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Gene Expression Commons: An Open Platform for Absolute Gene Expression Profiling

Figure 2

Structure and Workflow of Gene Expression Commons.

(A) Functional layers of Gene Expression Commons system. Users can select a Model of interest, and search for absolute gene expression through an intuitive web interface. A Model is a searchable category representing a biological context and displaying relationships among Populations. A Population contains several microarray data, which are biological replicates. Users can submit their own Populations, and design Models with a privacy control feature. (B) Seamless search flow at Gene Expression Commons. Gene Name Search provides absolute gene expression of a particular gene (path a). Expression Pattern Search provides a list of genes with expression patterns matching the expression pattern of interest designed by user (path b). From the list of genes, absolute expression of a particular gene is displayed with one click. From the absolute gene expression of a particular gene, the user can obtain a list of genes with the same expression pattern (path d).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0040321.g002