Perinatal Maternal Administration of Lactobacillus paracasei NCC 2461 Prevents Allergic Inflammation in a Mouse Model of Birch Pollen Allergy
Figure 4
Maternal L. paracasei supplementation results in up-regulation of regulatory markers.
(A) Expression of Foxp3 mRNA in lung tissue from offspring of L. paracasei-treated or sham-treated mothers. Foxp3 mRNA data is expressed relative to the housekeeping gene ALAS1. (B) Serum levels of TGF-β were determined by ELISA. Data is expressed as mean ± SEM (n ≥8; results represent pooled data from two independently performed experiments). **p<0.001; ***p<0.0001.