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Triadin/Junctin Double Null Mouse Reveals a Differential Role for Triadin and Junctin in Anchoring CASQ to the jSR and Regulating Ca2+ Homeostasis

Figure 4

Sections at right angle to triads in sternomastoid (top row) and soleus (bottom row) muscles illustrating changes in dimensions of the jSR cisternae relative to WT.

Compare with Table 1. C and D) In Jct-null muscles the triads are slightly smaller than WT in sternomastoid (A), but somewhat larger in soleus (compare B and D; E and F) in Tdn-null fibers the jSR cisternae are smaller in all muscles; G and H) in the double null the dimensions are further reduced. Bar: A–H, 0.1 µm.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0039962.g004