6-Arylpyrido[2,3-d]pyrimidines as Novel ATP-Competitive Inhibitors of Bacterial D-Alanine:D-Alanine Ligase
Figure 11
Calorimetric binding isotherms (▪) and the corresponding best fit model functions (–) for binding of a) 14 and b) 33 to DdlB at 37°C. r is the bound ligand to total protein concentration ratio.