The Enzymatic and Metabolic Capabilities of Early Life
Figure 2
Ancestral folds associated with metaconsensus enzyme functions.
Folds are given in the horizontal axis by their SCOP code [4]. Orange boxes indicate associations with metaconsensus enzyme reactions in the vertical axis. These folds (with ancestry values between 0% and 19%) were previously predicted to have originated before the establishment of the DNA genome [38]. All of the metaconsensus enzyme functions are associated with a number of ancient folds. The three transferases (EC codes 2.4.1.-, 2.7.1.-, and 2.7.7.-) are associated with the highest number of these ancient folds.