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Interleukin-15 Treatment Induces Weight Loss Independent of Lymphocytes

Figure 4

IL-15 induces weight loss independent of lymphocytes and in the absence of the common gamma chain (γc).

(A) Percentage of weight loss represented as a bar graph. (B) Picture shows excised visceral gonadal fat taken from representative female naïve, Ad-Control, and AdIL-15 treated RAG2−/−γc−/− mice. (C) Visceral gonadal fat pad in grams shown as a bar graph (n = 5 per group). (D) Food consumed per gram of mouse monitored for 5 consecutive days (n = 5 per group). *P<0.05, ***P<0.001.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0039553.g004