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Cancer-Associated Carbohydrate Antigens as Potential Biomarkers for Hepatocellular Carcinoma

Figure 2

Ratio of anti-glycan IgG levels to anti-Gb5 levels in serum from healthy individuals and patients with HCC.

Relative fluorescence ratios were calculated as the relative fluorescence intensity of each glycan analog divided by the relative fluorescence intensity of Gb5, and they are expressed as percentages in the figure. The figure shows the mean ratio ± standard deviation for each glycan. Asterisks indicate glycans in which the mean glycan:Gb5 IgG ratio was significantly higher in serum from patients with HCC (n = 155) than in serum from healthy individuals (n = 33). The p values were calculated with a Student’s t-test (*p<0.05; **p<0.01).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0039466.g002