Consensus Rules in Variant Detection from Next-Generation Sequencing Data
Figure 3
Distribution of read depth (DP) versus SNV quality score (QUAL) for the SNVs or indels selected for validation.
(a) Tier One SNVs (159 SNVs), (b) Tier Two SNVs (145 SNVs), (c) Tier One Indels (22 indels), and (d) Tier Two Indels (19 indels). Variants in blue denote successful validation, and variants in red denote failure in validation. In each panel, the vertical dash line indicates the cutoff value for QUAL, and the horizontal dash line indicates cutoff value for DP (see Point 2 in the main text and Table 1).