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Development of Novel Single-Stranded Nucleic Acid Aptamers against the Pro-Angiogenic and Metastatic Enzyme Heparanase (HPSE1)

Figure 8

OC MZ-6 cells cultured in medium supplemented with anti-heparanase antibody, 1.5 M short, 1.5 M long and 3.0 M aptamers.

The negative controls were represented as no inhibitor and a control mouse antibody. Figures are representative of the average of triplicate experiments and error bars show standard deviation of the mean.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0037938.g008