Integrative Gene Regulatory Network Analysis Reveals Light-Induced Regional Gene Expression Phase Shift Programs in the Mouse Suprachiasmatic Nucleus
Figure 1
Light pathway within the SCN and genes that involved in the process.
A) An illustration of light signal's progression through the core and shell of the SCN. Major functional groups are highlighted including membrane receptors, cellular signal pathways, immediate early gene activations, and circadian oscillator. B) A consolidated view of an SCN neuron. Genes listed were used in the qPCR assay, and focus on the circadian clock and genes involved in mediating its response to light. Definitive gene functions are shown in solid arrows. Implied gene functions are shown in dashed arrows.