Surfactant Protein D Deficiency in Mice Is Associated with Hyperphagia, Altered Fat Deposition, Insulin Resistance, and Increased Basal Endotoxemia
Figure 2
A) Mean body mass gain in male Spd−/− and wild-type mice fed on a 80% energy restricted diet for 18 weeks.
ANOVA of body mass gain after 18 weeks did not show any genotype difference. B) Mean body masses of Spd−/− and wild-type mice fed a 95% restricted low fat diet. The body masses in Spd−/− and wild-type mice were equal after 25 weeks of diet treatment. C) The masses of three fat pads from 32 week old mice fed a 95% restricted low fat diet. The total mean mass of the three pads and the retroperitoneal pads was equal in the two genotypes. The gonadal fat pad mass was decreased and the subcutaneous pad was increased in Spd−/− mice. * p = 0.003, ** p = 0.008. Data are means + or − SE, n = 6.