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AS03 Adjuvanted AH1N1 Vaccine Associated with an Abrupt Increase in the Incidence of Childhood Narcolepsy in Finland

Figure 1

The temporal associations of pandemic vaccination, onset of narcolepsy (with four different definitions), and August 16, 2010, i.e. the date when the Swedish Medical Agency published the press release on the observation on the association between narcolepsy and Pandemrix vaccination (vertical dotted line).

Panel top left is Recall = Parental/Patient recall when excessive daytime sleepiness (EDS) started; Panel top right is First contact = first contact to health care because of EDS; Panel bottom left is Referral = referral to specialist (paediatrician, neurologist); and Panel bottom right is Diagnosis = when diagnosis of narcolepsy was set.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0033536.g001