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Allotransplanted Neurons Used to Repair Peripheral Nerve Injury Do Not Elicit Overt Immunogenicity

Figure 5

MHC I immunoreactivity (red) in neuronal structure (NF-200, green).

For anatomical terminology, refer to Fig. 1E. (A) Increased MHC I immunoreactivity were observed in NG, DRG, and Schwann groups compared to the Sham group. DAPI (blue), 20×. Thickness = 15 um. (B) Axon regeneration estimated by NF-200 expressing axons. Axon density in distal stump was calculated and expressed as standard optical density (SOD) for each group. n = 3, 40× image of 10 um sections.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0031675.g005