Predicting Target DNA Sequences of DNA-Binding Proteins Based on Unbound Structures
Figure 5
An example where the template has a low structure similarity to the query.
This case demonstrates that using less similar templates still has the potential to produce satisfied results. This figure contains two proteins that share similar DNA-binding interface but have low global structure similarity (TM-score = 0.38). The Ψ-score of the predicted PWM to the annotated PWM using the orange protein (1MH3:A, MATA1_YEAST) as the query and the green protein (1SKN:P, SKN1_CAEEL) as the template is 0.18. Contact residues on both protein structures are plotted in sticks presentation.