Androgen Receptor Variants Occur Frequently in Castration Resistant Prostate Cancer Metastases
Figure 1
Characterization of the LuCaP 86.2 subcutaneous xenograft tumor.
(A) Western blot analysis of AR expression in LuCaP 86.2 and LuCaP 35 xenograft tumors. (B) IHC staining for the N- and C-terminal AR on LuCaP 86.2 (a and b) and LuCaP 35 (c and d) xenograft tumors. (C) IHC staining for PSA (e), PSMA (f), Chromogranin-A (g), Synaptophysin (h), Ki67 (i) and negative control (j) on LuCaP 86.2 xenograft. (D) IHC staining for PSA (k), PSMA (l), Chromogranin-A (m), Synaptophysin (n), Ki67 (o) and negative control (p) on LuCaP 35 xenograft. (original magnification x200, insert x400).