The Catechol-O-Methyltransferase (COMT) val158met Polymorphism Affects Brain Responses to Repeated Painful Stimuli
Figure 2
Genotype effects on pain-evoked brain activations.
A. Genotype effect on pain related activations, emerging for HIGH pain in the second run. Brain activations for the contrast met/met>val/val, overlaid on the MNI152 standard brain. Right side = right hemisphere. B. Significant activations from the between-subject analyses masked with regions in which val/val exhibited a reduction in BOLD signal in Run 2 as compared to Run 1.