Active Transport of Bile Acids Decreases Mucin 2 in Neonatal Ileum: Implications for Development of Necrotizing Enterocolitis
Figure 1
Increased ileal damage in mice with aberrant Muc2.
Representative H & E staining of ileal sections from neonatal (A) Winnie −/− DF, (B) Winnie +/+ DF, (C) Winnie −/− NEC and (D) Winnie +/+ NEC mouse pups. Winnie −/− and +/+ DF depict ileal damage scores of 0; Winnie −/− NEC depicts damage score of 2, moderate separation of submucosa and/or lamina propria; Winnie +/+ NEC depicts damage score of 3, severe separation of submucosa and/or lamina propria. Bars indicate 50 µm.