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Inflammatory Bowel Diseases Phenotype, C. difficile and NOD2 Genotype Are Associated with Shifts in Human Ileum Associated Microbial Composition

Figure 2

Targeted qPCR results for the C. coccoides-E. rectales group and for F. prausnitzii spp.

Boxplots of (panel A) the log2 C. coccoides-E. rectales group/total bacteria and (panel B) the log2 F. prausnitzii/total bacteria as a function of disease phenotype and NOD2 genotype assayed using qPCR are shown. The middle line represents the median, and the lower edge and the upper edge of the box represent the 25% and 75% quartiles. The bottom and top lines represent the minimum and maximum values, respectively. For the C. coccoides-rectales group, all 170 samples were assayed. For F. prausnitzii, 157 of 170 samples were assayed.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0026284.g002