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Magnetic Resonance Spectroscopy Detectable Metabolomic Fingerprint of Response to Antineoplastic Treatment

Figure 1

Inhibition of target signaling pathways in cancer cells following drug treatment.

Schematic of signaling pathways targeted by LY294002 and 17AAG and Western blots showing modulation of p-4E-BP1 and c-Raf (β-actin as loading control) levels following administration of DMSO (solvent control; C), LY294002 (L) or 17AAG (A).

Figure 1

doi: https://doi.org/10.1371/journal.pone.0026155.g001