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Hepcidin Is Involved in Iron Regulation in the Ischemic Brain

Figure 1

Expression of L-ferritin and H-ferritin in ischemic brain.

Rats were subjected to 60 min MCAO and 24 hour reperfusion. Contralateral and ipsilateral cerebral cortex (A,E), hippocampus (B,F) and corpus striatum (C,G) were isolated, homogenized, and analyzed for L- and H- ferritin by Western blotting. Representative ferritin blots and corresponding β-actin blots are shown on the top panel. The lower panel (D, H) shows the summary of L-ferritin and H-ferritin expression levels from three animals in each group. Results are presented as Mean ± SEM, n = 3. **p<0.01 v.s. contraleteral side, *p<0.05 v.s. contralateral side.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0025324.g001