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Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1)

Figure 5

Network of predicted miRNA-mRNA interactions.

(A) Regression-based method was used to predict the miRNAs (green circles) that are actively regulating mRNAs (red diamonds) in our dataset. (B&C) Validation of miRNA-mRNA interaction partners by RT-PCR using independent samples (n = 6) for IL-1ß(B) and IL-6 (C).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0022730.g005