Aberrant DNA Methylation Is Associated with Disease Progression, Resistance to Imatinib and Shortened Survival in Chronic Myelogenous Leukemia
Figure 4
Advanced stage of CML and resistance or intolerance to imatinib are associated with shortened survival.
Top graph, green, chronic phase; red, accelerated phase; black, blastic phase. Bottom graph, green, imatinib-responsive patients; red, patients resistant or intolerant to imatinib. The figure shows 90 CML patients (43 CP, 34 AP, 13 BP) from the imatinib era.