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Scaling Behavior of Human Locomotor Activity Amplitude: Association with Bipolar Disorder

Figure 4

Estimated means (±SEM) computed vulnerability index (VI) values in four groups of human subjects of increasing risk or presence of BD.

Low risk by GBI criteria (n = 35), healthy controls (n = 15), high-risk by GBI criteria (n = 35), and patients diagnosed with DSM-IV type-I BD who are currently clinically stable or euthymic (n = 15). Curve-fitting found that mean VI increased linearly across these groups (F [df = 3; 94] = 4.28, p = 0.007, controlling for sex and age).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0020650.g004