Rapid Reactivation of Extralymphoid CD4 T Cells during Secondary Infection
Figure 5
Impact of CD4+ T cells on viral titers during secondary infection.
BAL supernatants from memory, secondary infected, and GK1.5-treated secondary infected mice were injected into embryonated chicken eggs for determination of viral titers (see Materials and Methods). Samples from day 1, 2, and 4 post-secondary infection (with X-31 virus) were compared +/− GK1.5 treatment, with primary X-31 infection as control. Mean and SEM from the n = 3–4 mice per time points per group are indicated by the horizontal bar symbols and in the inset figure. A Kruskal-Wallis rank test was performed, with significant p values shown.