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Extending the Aerolysin Family: From Bacteria to Vertebrates

Figure 4

Domain organization of the Aerolysin/ETX pore-forming superfamily.

Proteins 1–4 are present in bacteria, 5–11 in Eukaryotes. Domain organization representatives: (1) alpha-toxin, gi:452163 [Clostridium septicum]; (2) Hemolysin-3, gi:2501300 [Aeromonas hydrophila]; (3) hypothetical protein BACUNI_04630, gi:160892167 [Bacteroides uniformis ATCC 8492]; (4) pXO2-60 protein, gi: 10956450 [Bacillus anthracis]; (5) hypothetical protein CAN71829, gi:147838248 [Vitis vinifera]; (6) ep37-L2, gi:2339973 [Cynops pyrrhogaster]; (7) Natterin-3 precursor, gi:75571591 [Thalassophryne nattereri]; (8) hypothetical protein NEMVEDRAFT_v1g221281, gi:156349328 [Nematostella vectensis]; (9) hypothetical protein LOC494812, gi:148223884 [Xenopus laevis]; (10) hypothetical protein LOC613112, gi:73853870 [Xenopus tropicalis]; (11) hypothetical protein LOC568775, gi:162139040 [Danio rerio].

Figure 4

doi: https://doi.org/10.1371/journal.pone.0020349.g004