Activation of Peroxisome Proliferator-Activated Receptor Gamma by Rosiglitazone Increases Sirt6 Expression and Ameliorates Hepatic Steatosis in Rats
Figure 5
Sirt6 knockdown diminished the effect of rosiglitazone (RGZ) to reduce hepatocyte lipid accumulation.
Values of triglyceride (TG) and free fatty acids (FFA) were normalized with respect to protein concentrations. Data are means±SEM (n = 6 per group). *p<0.05 vs control (CON; white bar), †p<0.05 vs FFA alone.