Murine Cytomegalovirus Infection of Neural Stem Cells Alters Neurogenesis in the Developing Brain
Figure 6
Differential expression of the transcription factor Oct4 in infected brains.
Brain-derived cells prepared from either infected or mock-infected animals were incubated with different MAbs for surface markers including CD15, CD24, and CD29. The cellular subsets were then analyzed for expression of the transcription factor Oct4 and compared with mock-infected brains in the histogram overlays. Histogram overlays show a blue line representing control neonates, an orange line MCMV infected, and a black line representing isotype for Oct4 staining. Data were derived from 3 independent experiments, n = 3–5 neonates.